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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf48
All Species:
13.64
Human Site:
S496
Identified Species:
30
UniProt:
Q9NWS1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWS1
NP_060385.2
579
65081
S496
R
S
K
N
E
K
V
S
R
K
S
T
S
Q
T
Chimpanzee
Pan troglodytes
XP_509318
760
85084
S677
R
S
K
N
E
K
V
S
R
K
S
T
S
Q
T
Rhesus Macaque
Macaca mulatta
XP_001085518
579
65125
S496
R
S
K
N
E
K
V
S
R
K
S
T
S
Q
T
Dog
Lupus familis
XP_855025
579
65071
A496
R
S
K
S
E
K
V
A
R
K
P
S
S
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6IRT3
573
64087
R494
W
K
G
D
K
L
P
R
K
S
T
Q
R
Q
I
Rat
Rattus norvegicus
Q9EQ10
573
63884
P494
R
S
K
D
D
K
G
P
R
K
S
T
K
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507285
579
64417
T496
R
R
K
R
E
K
V
T
I
K
S
S
C
Q
S
Chicken
Gallus gallus
Q5ZKL9
580
65236
Y494
N
V
H
Q
N
R
N
Y
R
E
M
G
K
L
S
Frog
Xenopus laevis
Q32N66
567
63030
E491
N
I
D
L
K
T
A
E
Q
V
K
N
K
P
C
Zebra Danio
Brachydanio rerio
Q1RMA6
568
62451
H485
G
Q
S
A
L
G
E
H
S
G
N
A
W
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178396
861
96268
N686
G
W
C
N
A
E
R
N
R
N
R
S
R
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
94.4
82.3
N.A.
69.2
68.7
N.A.
63.2
54.4
50
39.3
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
75.5
96.7
90.6
N.A.
81.3
80.6
N.A.
78.4
72
64.5
56.6
N.A.
N.A.
N.A.
N.A.
37.5
P-Site Identity:
100
100
100
73.3
N.A.
6.6
53.3
N.A.
53.3
6.6
0
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
73.3
N.A.
73.3
26.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
10
10
0
0
0
10
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
0
10
19
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
46
10
10
10
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
10
0
0
10
10
0
0
10
0
10
0
0
0
% G
% His:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
10
55
0
19
55
0
0
10
55
10
0
28
10
10
% K
% Leu:
0
0
0
10
10
10
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
19
0
0
37
10
0
10
10
0
10
10
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
10
0
0
10
0
% P
% Gln:
0
10
0
10
0
0
0
0
10
0
0
10
0
55
10
% Q
% Arg:
55
10
0
10
0
10
10
10
64
0
10
0
19
10
0
% R
% Ser:
0
46
10
10
0
0
0
28
10
10
46
28
37
0
19
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
10
37
0
0
46
% T
% Val:
0
10
0
0
0
0
46
0
0
10
0
0
0
0
0
% V
% Trp:
10
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _